A New Stochastic Model to Find the Insulin Secretion from Human Islets Using Exponential Distribution
Abstract
Many plant based products have been suggested as potential antidiabetic agents, but
few have been shown to be effective in treating the symptoms of Type 2 diabetes mellitus
(T2DM) in human studies, and little is known of their mechanisms of action. The effects of a
novel high molecular weight Gymnema sylvestre (GS) extract, Om Santal Adivasi (OSA) on
plasma insulin, C-peptide and glucose in a small cohort of patients with T2DM are reported
here. Oral administrationof OSA induced significant increases in circulating insulin and Cpeptide, which were associated with significant reductions in fasting and post-prandial blood
glucose. The results of insulin secretion from human islets of langerhans were compared
using the marginal distribution of a stretched Brownian motion
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